In Italy, “the virus no longer exists from a clinical point of view”

Alberto Zangrillo, Chief and Director of Intensive Care at San Raffaele Hospital in Milan on Italian state television: "The [test] swabs performed in the last ten days have results with an infinitesimal viral load from the quantitative point of view compared to the swabs performed on patients a month ago”.

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Some additional comments on the design of the study conducted by the University of Kentucky

While we are currently working on other urgent matters and have hardly any time to follow up on the the throat disinfection complex, let us - very briefly - make the following additional comments with regard to the study underway in Kentucky. If nothing else, they may serve as a mental check to the study investigators (who we will make aware of them, of course).

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Update on preventive throat disinfection / antisepsis to counter COVID-19

A clinical trial is now actively testing preventive throat disinfection / antisepsis to counter COVID-19 in hospital personnel. And a study confirming efficacy of one of the substances we mentioned as being effective against SARS-CoV-2 in vitro was published yesterday.

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International researchers pick up loico’s idea of throat disinfection to counter COVID-19

A group of researchers from the UK (Cardiff and Cambridge), the US (Denver, Colorado), Spain (Barcelona), and Canada (Ottawa) has now picked up the idea we have put forward almost exactly two months ago for preventive throat disinfection with virucidal agents that are known to be effective against coronaviruses and safe to use in the throat. The WHO should now even more seriously consider including it in its recommendations.

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And if COVID-19 were about to fuel the next big upswing in economic prosperity and quality of life?

COVID-19, many believe, has thrown the world into unprecedented disaster, and to those believing so, the future looks bleak at best. But what if the opposite will prove to be true? Speculation is a noble occupation, futures studies an academic discipline, so we hazard a brief preview of the enormous economic and societal gains for which the COVID-19 crisis may have just sown the seeds.

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Additional thoughts regarding the benefit of throat disinfection during COVID-19-like epidemics
Heinrich Wilhelm Gottfried von Waldeyer-Hartz, eponym of Waldeyer's tonsillar ring in the pharynx, considered “the first line of defense against exogenous aggressors”. Photograph: Wikipedia

Additional thoughts regarding the benefit of throat disinfection during COVID-19-like epidemics

While in recent weeks we have been focused on establishing and comprehending as deeply as possible the immunological "big picture" in viral epidemics from so far only partly interconnected evidence in the specialist literature, in order to derive actionable recommendations, we briefly summarize what has emerged in terms of feedback as well as additional insight with regard to our first article since it appeared.

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Chaos and COVID-19
Roman bronze bust of the late 1st century BC, assumed to represent Hesiod, thought to be a copy of a lost Greek original of ca. 200 BC. Museo Archeologico Nazionale, Naples. Photograph: Marie-Lan Nguyen

Chaos and COVID-19

COVID-19 has seemingly thrown the world into "chaos", taking away much of the safeness and certainty that had been taken for granted. When maneuvering in chaos, in order to not lose one's head, it helps to firmly keep in mind the logic of chaos.

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COVID-19: Why herd immunity will likely occur much sooner than currently expected

Intelligent if unconventional methods employed by researchers have likely enabled a more realistic view on the actual infection rate and the related questions of when herd immunity will be achieved and what the realistic death rate of COVID-19 actually is. Understanding the true dynamics of the pandemic is crucial to taking the most adequate policy decisions going forward.

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The logic of surviving the Coronavirus pandemic – executive summary

The following is a brief summary of our original article "The logic of surviving the Coronavirus pandemic". If the risk of dying from the infection is drastically reduced, the Coronavirus pandemic is immediately reduced to the status of a normal wave of influenza.

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