Update on COVID-19 and oral antisepsis

Yet oth­er researchers have come to con­clu­sions sim­i­lar to the one we pub­lished on March 161 in a paper pub­lished on June 23, 2020.2 The “Results” of their “dis­cus­sion paper” read:

Oral viral load of SARS-CoV-2 has been asso­ci­at­ed with the sever­i­ty of COVID-19, and thus, a reduc­tion in the oral viral load could be asso­ci­at­ed with a decrease in the sever­i­ty of the con­di­tion. Similarly, a decrease in the oral viral load would dimin­ish the amount of virus expelled and reduce the risk of trans­mis­sion, since (i) dur­ing the first 10 days, the virus main­ly accu­mu­lates at the nasal, oral, and pha­ryn­geal area; (ii) the num­ber of angiotensin-con­vert­ing enzyme (ACE2) recep­tor is greater in the sali­vary glands as com­pared with the lungs; and (iii) sali­vary droplets rep­re­sent the most rel­e­vant trans­mis­sion route. To reduce the oral viral load, anti­sep­tic agents may be used, although the evi­dence on its effi­ca­cy is indi­rect and weak.

A group of researchers from Italy has seem­ing­ly test­ed part of the hypoth­e­sis, with a stat­ed focus on viral trans­mis­sion pre­ven­tion, in a “pilot study” of at least 39 asymp­to­matic virus car­ri­ers in vivo.3 Their results, obtained with yet oth­er viru­ci­dals than those men­tioned by us, as well as their delib­er­a­tions based on their own results and the avail­able lit­er­a­ture, may appear to sup­port loico’s ini­tial idea. We see sev­er­al rea­sons for cau­tion with regard to the study design, how­ev­er, where exact pro­ce­dures observed would need sig­nif­i­cant fur­ther clar­i­fi­ca­tion. Specifically, the authors do not dis­cuss why they believed that estab­lish­ing a con­trol group was not nec­es­sary, and what prob­a­bil­i­ty they assigned, and why, to the asymp­to­matic car­ri­ers being test­ed neg­a­tive any­way after the three days dur­ing which they were required to apply oral anti­sep­sis.

Similar to the authors cit­ed above, the poten­tial for a role in indi­vid­ual health preser­va­tion is express­ly con­sid­ered in the “Results”:

Prevention of inner spread. It is also pos­si­ble to con­sid­er that from the sali­va (with its high viral con­tent) while the mouth is act­ing as a viral grow­ing cham­ber, the viral par­ti­cles may be aerosolized into the lungs. The con­tain­ment of viral growth in the mouth may also halt the spread­ing of the virus from the mouth to the tra­chea and into the bronchial tree.

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  1. See https://loico.com/the-logic-of-surviving-the-coronavirus-pandemic/; https://loico.com/additional-thoughts-regarding-benefit-throat-disinfection-covid-19-like-epidemics/; https://loico.com/international-researchers-pick-up-loicos-idea-of-throat-disinfection-to-counter-covid-19/; https://loico.com/update-on-preventive-throat-disinfection-antisepsis-to-counter-covid-19/; https://loico.com/some-additional-comments-on-the-design-of-the-study-conducted-by-the-university-of-kentucky/[]
  2. https://link.springer.com/article/10.1007/s00784-020-03413-2[]
  3. https://medclinres.org/pdfs/2020/virucidals-control-the-presence-of-covid-in-mouth-saliva-mcr-20.pdf[]
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After it has come to light that “Black Lives Matter” is a marxist – and blatantly racist – organization that could not care less about equal opportunity but that, according to rally signs exhibited by “activists”, simply wants to “kill” or “eat the rich”, now the climate change scare appears to be crumbling to pieces as well: It appears we now have the Edward Snowden of climate change alarmism.

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After it has come to light that “Black Lives Matter” is a marxist – and blatantly racist – organization that could not care less about equal opportunity but that, according to rally signs exhibited by “activists”, simply wants to “kill” or “eat the rich”, now the climate change scare appears to be crumbling to pieces as well: It appears we now have the Edward Snowden of climate change alarmism.